Sodium gentisate
Names
[ CAS No. ]:
4955-90-2
[ Name ]:
Sodium gentisate
[Synonym ]:
KAD 3213
[3H]-Silodosin
EINECS 225-598-2
[14C]-Silodosin
UNII-CUZ39LUY82
MFCD00016504
Urief
1-(3-Hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-7-indolinecarboxamide
1-(3-hydroxypropyl)-5-[(2R)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboxamide
Rapaflo
1H-Indole-7-carboxamide, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-
Silodyx
Silodosin
KMD-3213
Chemical & Physical Properties
[ Boiling Point ]:
406.9ºC at 760 mmHg
[ Melting Point ]:
>220ºC (dec)
[ Molecular Formula ]:
C7H5NaO4
[ Molecular Weight ]:
176.102
[ Flash Point ]:
214ºC
[ Exact Mass ]:
176.008560
[ PSA ]:
80.59000
[ Storage condition ]:
-20?C Freezer
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LY3860000
- CHEMICAL NAME :
- Gentisic acid, monosodium salt
- CAS REGISTRY NUMBER :
- 4955-90-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C7-H5-O4.Na
- MOLECULAR WEIGHT :
- 176.11
- WISWESSER LINE NOTATION :
- OVR BQ EQ &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3735 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 43,334,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 146,466,1952
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
LY3860000
Precursor & DownStream
Precursor
DownStream
Articles
Rapid Commun. Mass Spectrom. 27(1) , 103-8, (2013)
Although matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) is an important method for post-translational modification (PTM) analysis, the conventional matrices, 2,5-dihydroxybenz...
Quantitative imaging of a therapeutic peptide in biological tissue sections by MALDI MS.Bioanalysis 5(5) , 603-12, (2013)
Therapeutic peptides and proteins are being increasingly explored as potential therapeutic agents for molecular-targeted therapy, and the requirement for quantitative bioanalytical tools for such mole...
Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.PLoS ONE 7(8) , e43696, (2012)
Siderocalin (also lipocalin 2, NGAL or 24p3) binds iron as complexes with specific siderophores, which are low molecular weight, ferric ion-specific chelators. In innate immunity, siderocalin slows th...