Salinazid

Names

[ CAS No. ]:
495-84-1

[ Name ]:
Salinazid

[Synonym ]:
AURORA KA-4878
1-Isonicotinoyl-2-salicylidenehydrazine
ISOPROPYLTHIOXANTHONE
AT-1
Salinazid
ITX
SPEEDCURE ITX
MFCD00055658

Biological Activity

[Description]:

Salinazid is an antituberculous compound[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Blokhina, Svetlana, et al. Antituberculous isoniazid and some related compounds: solubility in pharmaceutically significant solvents and sublimation.

Chemical & Physical Properties

[ Density]:
1.24 g/cm3

[ Boiling Point ]:
401.8ºC at 760mmHg

[ Melting Point ]:
232-233ºC

[ Molecular Formula ]:
C₁₃H₁₁N₃O₂

[ Molecular Weight ]:
241.24500

[ Flash Point ]:
196.8ºC

[ Exact Mass ]:
241.08500

[ PSA ]:
74.58000

[ LogP ]:
1.94200

[ Index of Refraction ]:
1.623

[ Storage condition ]:
-196°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NS1790010

CHEMICAL NAME :: Isonicotinic acid, (o-hydroxybenzylidene)hydrazide

CAS REGISTRY NUMBER :: 495-84-1

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H11-N3-O2

MOLECULAR WEIGHT :: 241.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,1036,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >20 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,442,1954/1955

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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