Benzohydroxamic acid

Names

[ CAS No. ]:
495-18-1

[ Name ]:
Benzohydroxamic acid

[Synonym ]:
EINECS 207-797-6
Benzohydroxamic acid
MFCD00002109
BENZOHYROXAMICACID
n-hydroxy-benzamid
benzoylhydroxamic acid
BHAM
benzoyl hydroxylamine
benzohydroxamate
N-Hydroxy-benzamide
hydroxy benzamide
N-Hydroxybenzamide
Benzamide, N-hydroxy-
benzhydroxamic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
327.1ºC at 760 mmHg

[ Melting Point ]:
126-130 °C(lit.)

[ Molecular Formula ]:
C₇H₇NO₂

[ Molecular Weight ]:
137.136

[ Flash Point ]:
201ºC

[ Exact Mass ]:
137.047684

[ PSA ]:
49.33000

[ LogP ]:
0.26

[ Index of Refraction ]:
1.578

[ Stability ]:
Moisture and Temperature Sensitive

[ Water Solubility ]:
22 g/L (6 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DF9650000

CHEMICAL NAME :: Benzohydroxamic acid

CAS REGISTRY NUMBER :: 495-18-1

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C7-H7-N-O2

MOLECULAR WEIGHT :: 137.15

WISWESSER LINE NOTATION :: QMVR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 333 ug/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19(Suppl 21),2,1992

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R68

[ Safety Phrases ]:
S45-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DF9650000

[ HS Code ]:
29280090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29280090

Articles

Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.

Bioorg. Med. Chem. 18 , 2225-31, (2010)

There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one pa...

Intermediate analogue inhibitors of mandelate racemase: N-Hydroxyformanilide and cupferron.

Bioorg. Med. Chem. Lett. 17 , 105-8, (2007)

Mandelate racemase (MR) catalyzes the 1,1-proton transfer that interconverts the enantiomers of mandelate. The transition state/intermediate analogues N-hydroxyformanilide (K(i)=2.79+/-0.19 microM) an...

Dephosphorylation reactions of mono-, di-, and triesters of 2,4-dinitrophenyl phosphate with deferoxamine and benzohydroxamic acid.

J. Org. Chem. 77(23) , 10907-13, (2012)

This work presents a detailed kinetic and mechanistic study of biologically interesting dephosphorylation reactions involving the exceptionally reactive nucleophilic group, hydroxamate. We compare res...