penflufen

Names

[ CAS No. ]:
494793-67-8

[ Name ]:
penflufen

[Synonym ]:
(+/-)-N-{2-[1,3-dimethylbutyl] phenyl}-5-fluoro-1,3-dimethyl-lH-pyrazole-4-carboxamide
rac-5-fluoro-1,3-dimethyl-N-{2-[(2R)-4-methylpentan-2-yl]phenyl}-1H-pyrazole-4-carboxamide
Thiourea,N-[2,6-bis(1-methylpropyl)phenyl]-N'-(1,1-dimethylethyl)
N-(2,6-di-sec.-butyl-phenyl)-N'-tert.-butyl-thiourea
5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide
2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide
N-(2.6-Di-sec.-butyl-phenyl)-N'-tert.-butyl-thioharnstoff
5-Fluoro-1,3-dimethyl-N-[2-(4-methyl-2-pentanyl)phenyl]-1H-pyrazo le-4-carboxamide
N-[2-(1,3-dimethylbutyl)phenyl]-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide
N-(2-(1,3-dimethyl-butyl)-phenyl)-1,3-dimethyl-5-fluoro-1H-pyrazole-4-carboxylic acid amide

Biological Activity

[Description]:

Penflufen is a highly efficient, broad-spectrum succinate dehydrogenase inhibitor (SDHI). Penflufen can be used as a fungicide and has broad bioactivity against many fungal diseases, including potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanut and other similar fungal diseases[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Fang K, et al. Systematic evaluation of chiral fungicide penflufen for the bioactivity improvement and input reduction using alphafold2 models and transcriptome sequencing. J Hazard Mater. 2022 Oct 15;440:129729.

Chemical & Physical Properties

[ Density]:
1.128g/cm3

[ Boiling Point ]:
381.002ºC at 760 mmHg

[ Molecular Formula ]:
C18H24FN3O

[ Molecular Weight ]:
317.40

[ Flash Point ]:
184.224ºC

[ Exact Mass ]:
317.19000

[ PSA ]:
50.41000

[ LogP ]:
4.65350

[ Index of Refraction ]:
1.555

MSDS

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H410

[ Precautionary Statements ]:
P273-P501

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ RIDADR ]:
UN 3077 9 / PGIII

Synthetic Route