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sodium O-acetylsalicylate

Names

[ CAS No. ]:
493-53-8

[ Name ]:
sodium O-acetylsalicylate

[Synonym ]:
Acetylsalicylic acid sodium salt
Sodium O-acetylsalicylate
Sodium acetylsalicylic acid
Sodium acetylsalicylate
Aspirin sodium
Salicylic acid,acetate,sodium salt
ASA sodium salt
EINECS 207-777-7
sodium salt of acetylsalicylic acid
O-Acetylsalicylic acid,sodium salt
Sodium aspirin
aspirin sodium salt
2-acetoxybenzoic acid sodium salt

Chemical & Physical Properties

[ Boiling Point ]:
321.4ºC at 760mmHg

[ Molecular Formula ]:
C9H7NaO4

[ Molecular Weight ]:
202.13900

[ Flash Point ]:
131.2ºC

[ Exact Mass ]:
202.02400

[ PSA ]:
66.43000

[ Vapour Pressure ]:
0.000124mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VO0875000
CHEMICAL NAME :
Salicylic acid, acetate, sodium salt
CAS REGISTRY NUMBER :
493-53-8
LAST UPDATED :
199012
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C9-H7-O4.Na
MOLECULAR WEIGHT :
202.15
WISWESSER LINE NOTATION :
OVR BOV1 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human
DOSE/DURATION :
306 ug/kg
TOXIC EFFECTS :
Blood - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
730 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
909 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Host-mediated assay
TEST SYSTEM :
Rodent - rat Cells - not otherwise specified
DOSE/DURATION :
300 mg/kg
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 24,219,1975

Synthetic Route

Precursor & DownStream


Related Compounds

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