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2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid

Names

[ CAS No. ]:
490-20-0

[ Name ]:
2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid

[Synonym ]:
truxillic acid
2c,4t-Diphenyl-cyclobutan-1r,3t-dicarbonsaeure
1,3-Cyclobutanedicarboxylic acid, 2,4-diphenyl-
2,4-Diphenyl-1,3-cyclobutanedicarboxylic acid
2,4-diphenyl-cyclobutane-1,3-dicarboxylic acid
2,4-diphenylcyclobutane-1,3-dicarboxylic acid

Biological Activity

[Description]:

α-Truxillic acid is form by the dimerization of two molecules of α-trans-cinnamic acid, with anti-inflammatory activities[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Chi YM, et al. Antinociceptive activities of alpha-truxillic acid and beta-truxinic acid derivatives. Biol Pharm Bull. 2006 Mar;29(3):580-4.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
470.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16O4

[ Molecular Weight ]:
296.317

[ Flash Point ]:
252.4±25.2 °C

[ Exact Mass ]:
296.104858

[ PSA ]:
74.60000

[ LogP ]:
3.57

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.629

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds