Methyl 2-sulfanylbenzoate
Names
[ CAS No. ]:
4892-02-8
[ Name ]:
Methyl 2-sulfanylbenzoate
[Synonym ]:
Methyl 2-Mercaptobenzoate
2-Mercaptobenzoic Acid Methyl Ester
Thiosalicylic Acid Methyl Ester
Methyl 2-sulfanylbenzoate
Methyl thiosalicylate
Benzoic acid, 2-mercapto-, methyl ester
EINECS 232-189-9
MFCD00060678
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
261.9±23.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H8O2S
[ Molecular Weight ]:
168.213
[ Flash Point ]:
161.5±10.5 °C
[ Exact Mass ]:
168.024506
[ PSA ]:
65.10000
[ LogP ]:
2.69
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.574
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DH3500000
- CHEMICAL NAME :
- Benzoic acid, o-mercapto-, methyl ester
- CAS REGISTRY NUMBER :
- 4892-02-8
- BEILSTEIN REFERENCE NO. :
- 0956859
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H8-O2-S
- MOLECULAR WEIGHT :
- 168.22
- WISWESSER LINE NOTATION :
- 1SVR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DH3500000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Nucl. Med. Biol. 42(1) , 28-37, (2014)
Ghrelin is an endogenous hormone present in blood. It is released from the oxyntic cells (X/A-like cells) of the stomach and fundus and can exist in two forms: as an acylated and des-acylated ghrelin....
A chiral thioxanthone as an organocatalyst for enantioselective [2+2] photocycloaddition reactions induced by visible light.Angew. Chem. Int. Ed. Engl. 53(17) , 4368-71, (2014)
Thioxanthone 1, which was synthesized in a concise fashion from methyl thiosalicylate, exhibits a significant absorption in the visible light region. It allows for an efficient enantioselective cataly...
Novel alternative for the N-S bond formation and its application to the synthesis of benzisothiazol-3-ones.Org. Lett. 8(21) , 4811-3, (2006)
[reaction: see text] The synthesis of a series of benzisothiazolone derivatives starting from the readily available methyl thiosalicylate is presented. The key cyclization step features the formation ...