1,3-dithiolane
Names
[ CAS No. ]:
4829-04-3
[ Name ]:
1,3-dithiolane
[Synonym ]:
1,3-Dithiacyclopentane
1,3-DITHIOLANE
MFCD00041425
[1,3]Dithiolan
1',3'-dithiolane
Chemical & Physical Properties
[ Density]:
1.235
[ Boiling Point ]:
83-84°C 35mm
[ Melting Point ]:
68ºC
[ Molecular Formula ]:
C3H6S2
[ Molecular Weight ]:
106.21000
[ Flash Point ]:
68°C
[ Exact Mass ]:
105.99100
[ PSA ]:
50.60000
[ LogP ]:
1.42390
[ Index of Refraction ]:
1.599
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JP0511000
- CHEMICAL NAME :
- 1,3-Dithiolane
- CAS REGISTRY NUMBER :
- 4829-04-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C3-H6-S2
- MOLECULAR WEIGHT :
- 106.21
- WISWESSER LINE NOTATION :
- T5S CSTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,235,1982
Safety Information
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
3334
[ RTECS ]:
JP0511000
[ HS Code ]:
2934999090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
J. Org. Chem. 76(9) , 3274-85, (2011)
An unprecedented and highly diastereoselective 6-endo-trig cyclization of 2-alkenyl-1,3-dithiolanes has been developed yielding trans-decalins, an important scaffold present in numerous di- and triter...
gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.Chem. Commun. (Camb.) , 654, (2005)
2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridiniu...
Alpha-keto amide peptides: a synthetic strategy to resin-bound peptide isosteres for protease inhibitor screening on solid support.J. Comb. Chem. 6(2) , 181-95, (2004)
A synthetic strategy for the formation of resin-bound internal alpha-keto amide peptides suitable for protease inhibitor screening on solid support is presented. This general approach is based on the ...