3-(Phenylmethoxy)-1,2-propanediol
Names
[ CAS No. ]:
4799-67-1
[ Name ]:
3-(Phenylmethoxy)-1,2-propanediol
[Synonym ]:
3-(Benzyloxy)propane-1,2-diol
3-Benzyloxy-1,2-propanediol
(±)-Glycerol 1-benzyl ether
1-O-Benzyl-rac-glycerol
Chemical & Physical Properties
[ Density]:
1.16 g/cm3
[ Boiling Point ]:
355.1ºC at 760 mmHg
[ Molecular Formula ]:
C10H14O3
[ Molecular Weight ]:
182.21600
[ Flash Point ]:
168.6°C
[ Exact Mass ]:
182.09400
[ PSA ]:
49.69000
[ LogP ]:
0.55640
[ Index of Refraction ]:
n20/D 1.533
[ Storage condition ]:
Refrigerator
[ Stability ]:
Stable. Hygroscopic. Combustible. Incompatible with strong oxidizing agents.
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY3180000
- CHEMICAL NAME :
- 1,2-Propanediol, 3-benzyloxy-
- CAS REGISTRY NUMBER :
- 4799-67-1
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H14-O3
- MOLECULAR WEIGHT :
- 182.24
- WISWESSER LINE NOTATION :
- Q1YQ1O1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1650 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 105,450,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1820 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,470,1948
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TY3180000
[ HS Code ]:
2909499000
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909499000
[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Biophys. J. 89(3) , 1780-8, (2005)
Tethered membranes have been proven during recent years to be a powerful and flexible biomimetic platform. We reported in a previous article on the design of a new architecture based on the self-assem...
Chiral ligand exchange micellar electrokinetic chromatography using borate anion as a central ion.Electrophoresis 26(20) , 3884-9, (2005)
Three compounds having 1,2-diol structure (1-phenyl-1,2-ethanediol, 3-phenoxy-1,2-propanediol, and 3-benzyloxy-1,2-propanediol) were enantioseparated by ligand exchange MEKC using (5S)-pinanediol (SPD...
Identification of aquaporin 4 inhibitors using in vitro and in silico methods.Bioorg. Med. Chem. 17 , 411-417, (2009)
The in vitro inhibitory effects and in silico docking energies of 18 compounds with respect to aquaporin 4 (AQP4) were investigated. More than half of the compounds tested showed inhibitory activity i...