Ethyl 5-chloro-1H-indole-2-carboxylate

Names

[ Name ]:
Ethyl 5-chloro-1H-indole-2-carboxylate

[Synonym ]:
Ethyl 5-chloroindole-2-carboxylate
5-Chloroindole-2-carboxylic acid ethyl
5-Chloroindole-2-carboxylic Acid Ethyl Ester
1H-Indole-2-carboxylic acid, 5-chloro-, ethyl ester
5-chloro-2-Indolecarboxylic Acid Ethyl Ester
EINECS 225-345-6
Ethyl 5-chloro-1H-indole-2-carboxylate
MFCD00005610

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
375.0±22.0 °C at 760 mmHg

[ Melting Point ]:
166-168 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₀ClNO₂

[ Molecular Weight ]:
223.656

[ Flash Point ]:
180.6±22.3 °C

[ Exact Mass ]:
223.040009

[ PSA ]:
42.09000

[ LogP ]:
3.89

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.630

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Antiallergic agents. 3. N-(1H-tetrazol-5-yl)-2-pyridinecarboxamides.

J. Med. Chem. 27(2) , 125-28, (1984)

A series of N-tetrazolylpyridinecarboxamides was prepared and evaluated for antiallergic activity by the passive cutaneous anaphylaxis (PCA) assay. From the structure-activity relationships (SAR) of t...