Digitolutein

Names

[ CAS No. ]:
477-86-1

[ Name ]:
Digitolutein

[Synonym ]:
2-hydroxy-1-methoxy-3-methyl-anthraquinone
2-Hydroxy-1-methoxy-3-methyl-anthrachinon
1-methoxy-2-hydroxy-3-methylanthraquinone
3-hydroxy-4-methoxy-2-methylanthraquinone
Digitolutein
2-hydroxy-1-methoxy-3-methyl-9,10-anthraquinone

Biological Activity

[Description]:

Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of Plasmodium falciparum with an IC50 value of 12.92 μg/mL. Digitolutein can be used for the research of infection[1].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

Digitolutein 在 0、5、15、20、25 和 30 μg/mL 浓度时分别抑制 18.5%、43.23%、53.18%、60.76%、75.98% 和 82.51% 的镰状疟原虫生长[1]。

[References]

[1]. Koumaglo K, et al. Effects of three compounds extracted from Morinda lucida on Plasmodium falciparum. Planta Med. 1992 Dec;58(6):533-4.

Chemical & Physical Properties

[ Density]:
1.356g/cm3

[ Boiling Point ]:
493.6ºC at 760mmHg

[ Molecular Formula ]:
C₁₆H₁₂O₄

[ Molecular Weight ]:
268.26400

[ Flash Point ]:
189.4ºC

[ Exact Mass ]:
268.07400

[ PSA ]:
63.60000

[ LogP ]:
2.48460

[ Vapour Pressure ]:
2.29E-10mmHg at 25°C

[ Index of Refraction ]:
1.649

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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