Chalinasterol

Names

[ CAS No. ]:
474-63-5

[ Name ]:
Chalinasterol

[Synonym ]:
24-methylencholesterol
Cholesterol, 24-methylene-
Chalinasterol

Biological Activity

[Description]:

24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology[1][2][3].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Tabas I, et al. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction. J Clin Invest. 1989 Dec;84(6):1713-21.

[2]. Sun Y, et al. Sterols from Mytilidae show anti-aging and neuroprotective effects via anti-oxidative activity. Int J Mol Sci. 2014 Nov 25;15(12):21660-73.

[3]. Chakrabarti P, et al. Changes in Honey Bee Head Proteome in Response to Dietary 24-Methylenecholesterol. Insects. 2020 Oct 29;11(11):743.

Chemical & Physical Properties

[ Density]:
0.98g/cm3

[ Boiling Point ]:
490.3ºC at 760mmHg

[ Molecular Formula ]:
C₂₈H₄₆O

[ Molecular Weight ]:
398.66400

[ Flash Point ]:
213.8ºC

[ Exact Mass ]:
398.35500

[ PSA ]:
20.23000

[ LogP ]:
7.55480

[ Vapour Pressure ]:
1.14E-11mmHg at 25°C

[ Index of Refraction ]:
1.528

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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