3-Methoxy-2-cyclopenten-1-one

Names

[ Name ]:
3-Methoxy-2-cyclopenten-1-one

[Synonym ]:
3-Methoxycyclopent-2-enone
3-Methoxy-2-cyclopenten-1-one
1-methoxy-2-cyclopenten-1-one
3-methoxy-cyclopent-2-en-1-one
3-methoxycyclopent-2-ene-1-one
MFCD00192267
2-Cyclopenten-1-one, 3-methoxy-
3-Methoxycyclopent-2-en-1-one
3-methoxy-2-cyclopentene-1-one

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
214.9±29.0 °C at 760 mmHg

[ Melting Point ]:
49-53ºC(lit.)

[ Molecular Formula ]:
C₆H₈O₂

[ Molecular Weight ]:
112.127

[ Flash Point ]:
96.5±17.8 °C

[ Exact Mass ]:
112.052429

[ PSA ]:
26.30000

[ LogP ]:
-0.04

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.467

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Synthesis and structure-activity relationship of cyclopentenone oximes as novel inhibitors of the production of tumor necrosis factor-α.

Bioorg. Med. Chem. Lett. 24(13) , 2807-10, (2014)

3-Alkyl-2-aryl-2-cyclopenten-1-one oxime derivatives (1) were studied as a novel class of inhibitors of tumor necrosis factor α (TNF-α) with regard to synthesis and in vitro SAR inhibition of TNF-α. T...

Stereoselective α-quaternization of 3-methoxycycloalk-2-enones via 1,4-diastereoinduction of alkoxy dienolates.

J. Org. Chem. 77(2) , 1202-7, (2012)

The alkylation of dienolates generated from 3-methoxycycloalk-2-enones having a 3'-hydroxyl alkenyl chain provides the corresponding quaternized cycloalkenones in a highly diastereoselective manner. T...

Expanding the scope of asymmetric electrophilic atom-transfer reactions: titanium- and ruthenium-catalyzed hydroxylation of beta-ketoesters.

Proc. Natl. Acad. Sci. U. S. A. 101(16) , 5810-4, (2004)

The enantioselective formation of a quaternary stereogenic center coinciding with a hydroxylation process is a very rare reaction from a homogeneous catalysis point of view. Indeed, to our knowledge, ...