thialbarbital
Names
[ CAS No. ]:
467-36-7
[ Name ]:
thialbarbital
[Synonym ]:
Tialbarbitale [DCIT]
5-allyl-5-cyclohex-2-enyl-2-thioxo-dihydro-pyrimidine-4,6-dione
Thialpenton
5-Allyl-5-cyclohex-2-enyl-2-thio-barbitursaeure
Thialbarbitalum [INN-Latin]
Thialbarbital
Tialbarbital [INN-Spanish]
Thialbarbitone
4,6(1H,5H)-Pyrimidinedione,5-(2-cyclohexen-1-yl)dihydro-5-(2-propenyl)-2-thioxo
Thialbital,5-Allyl-5-<cyclohexen-(2)-yl>-2-thio-barbitursaeure
Kemithal
Thiohexallymalum
5-allyl-5-cyclohex-2-enyl-2-thio-barbituric acid
EINECS 207-390-3
Chemical & Physical Properties
[ Density]:
1.25g/cm3
[ Molecular Formula ]:
C13H16N2O2S
[ Molecular Weight ]:
264.34300
[ Exact Mass ]:
264.09300
[ PSA ]:
97.27000
[ LogP ]:
1.98790
[ Index of Refraction ]:
1.606
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CP8400000
- CHEMICAL NAME :
- Barbituric acid, 5-allyl-5-(2-cyclohexen-1-yl)-2-thio-
- CAS REGISTRY NUMBER :
- 467-36-7
- LAST UPDATED :
- 199007
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H16-N2-O2-S
- MOLECULAR WEIGHT :
- 264.37
- WISWESSER LINE NOTATION :
- T6VMYMV FHJ CUS F2U1 F- CL6UTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 106,437,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 384 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FSTEAI Farmaco. Scienza e Tecnica. (Pavia, Italy) V.1-7, 1946-52. For publisher information, see FRPSAX. Volume(issue)/page/year: 3,269,1948
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 390 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 1,215,1946