CARBIPHENE HYDROCHLORIDE
Names
[ CAS No. ]:
467-22-1
[ Name ]:
CARBIPHENE HYDROCHLORIDE
[Synonym ]:
Etymide hydrochloride
Etomide hydrochloride
Bandol
Carbiphene hydrochloride
Carbiphene HCl
Jubalon
Carbifene hydrochloride
Carbifene
Chemical & Physical Properties
[ Boiling Point ]:
566.3ºC at 760 mmHg
[ Molecular Formula ]:
C28H35ClN2O2
[ Molecular Weight ]:
467.04300
[ Flash Point ]:
296.3ºC
[ Exact Mass ]:
466.23900
[ PSA ]:
32.78000
[ LogP ]:
5.40160
[ Vapour Pressure ]:
7.67E-13mmHg at 25°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB8400000
- CHEMICAL NAME :
- Acetamide, 2-ethoxy-N-methyl-N-(2-(methylphenethylamino)ethyl)-2 ,2-diphenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 467-22-1
- LAST UPDATED :
- 199007
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C28-H34-N2-O2.Cl-H
- MOLECULAR WEIGHT :
- 467.10
- WISWESSER LINE NOTATION :
- 2OXR&R&VN1&2M2R D1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 2 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 6,547,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 370 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 154,484,1965