Hedragonic acid

Names

[ CAS No. ]:
466-02-4

[ Name ]:
Hedragonic acid

[Synonym ]:
MFCD20260862

Biological Activity

[Description]:

Hedragonic acid is an oleane-type triterpenoid compound, which can be isolated from the stems and roots of the southern snake vine. Hedragonic acid is a ligand and agonist for FXR. Hedragonic acid protected mice from liver damage caused by acetaminophen overdose and reduced liver inflammation[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Research Areas >> Inflammation/Immunology

[References]

[1]. Lu Y, et al. Identification of an Oleanane-Type Triterpene Hedragonic Acid as a Novel Farnesoid X Receptor Ligand with Liver Protective Effects and Anti-inflammatory Activity. Mol Pharmacol. 2018 Feb;93(2):63-72.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₄O₃

[ Molecular Weight ]:
440.66

[ Exact Mass ]:
440.32900

[ PSA ]:
54.37000

[ LogP ]:
7.05170

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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