Marrubiin

Names

[ CAS No. ]:
465-92-9

[ Name ]:
Marrubiin

[Synonym ]:
Marrubiin I
MarrubiuM bitter

Biological Activity

[Description]:

Marrubiin, isolated from Marrubium vulgare, exhibits vasorelaxant and antioedematogenic activity. Marrubiin alleviates diabetic symptoms in animals[1][2][3].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. El Bardai S, et al. The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare. Planta Med. 2003 Jan;69(1):75-7.

[2]. Stulzer HK, et al. Antioedematogenic effect of marrubiin obtained from Marrubium vulgare. J Ethnopharmacol. 2006 Dec 6;108(3):379-84.

[3]. N.Mnonopi, et al. Marrubiin, a constituent of Leonotis leonurus, alleviates diabetic symptoms. Phytomedicine. 2012 Apr.

Chemical & Physical Properties

[ Density]:
1.152g/cm3

[ Boiling Point ]:
465.2ºC at 760mmHg

[ Melting Point ]:
159-162ºC

[ Molecular Formula ]:
C₂₀H₂₈O₄

[ Molecular Weight ]:
332.43400

[ Flash Point ]:
235.2ºC

[ Exact Mass ]:
332.19900

[ PSA ]:
59.67000

[ LogP ]:
3.72120

[ Vapour Pressure ]:
1.87E-09mmHg at 25°C

[ Index of Refraction ]:
1.537

Safety Information

[ Risk Phrases ]:
25

[ Safety Phrases ]:
1-22-45

[ RIDADR ]:
UN 2811