capsanthin

Names

[ CAS No. ]:
465-42-9

[ Name ]:
capsanthin

[Synonym ]:
(3R,3'S,5'R)-3,3'-Dihydroxy-b,k-caroten-6'-one
capsanthin
β,κ-Caroten-6'-one, 3,3'-dihydroxy-, (3R,3'S,5'R)-
Paprika Extract,Vegetable oil
Paprika Extract
(2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-1-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethyl-2,4,6,8,10,12,14,16,18-nonadecanonaen-1-one
(3R,3'S,5'R)-3,3'-Dihydroxy-β,κ-caroten-6'-one

Biological Activity

[Description]:

Capsanthin is a carotenoid that has been found in C. annuum. Capsanthin has antioxidant[1]、antitumor[2] and anti-inflammatory[3] effects.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

Research Areas >> Inflammation/Immunology

[References]

[1]. Kim JS, et al. Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communication. Chem Biol Interact. 2016 Jul 25;254:146-55.

[2]. Narisawa T, et al. Prevention of N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin and capsanthin-rich paprika juice. Proc Soc Exp Biol Med. 2000 Jun;224(2):116-22.

[3]. Horie S, et al. Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory response. Lipids. 2010 Aug;45(8):713-21.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
726.6±60.0 °C at 760 mmHg

[ Melting Point ]:
177-178ºC

[ Molecular Formula ]:
C₄₀H₅₆O₃

[ Molecular Weight ]:
584.871

[ Flash Point ]:
407.2±29.4 °C

[ Exact Mass ]:
584.422974

[ PSA ]:
57.53000

[ LogP ]:
9.90

[ Vapour Pressure ]:
0.0±5.4 mmHg at 25°C

[ Index of Refraction ]:
1.563

MSDS

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Safety Information

[ HS Code ]:
3203001990

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 3203001990