2,5-DiMethyl Celecoxib

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
516.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆F₃N₃O₂S

[ Molecular Weight ]:
395.399

[ Flash Point ]:
266.3±32.9 °C

[ Exact Mass ]:
395.091522

[ PSA ]:
86.36000

[ LogP ]:
4.67

[ Appearance of Characters ]:
white to beige

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Storage condition ]:
room temp

[ Water Solubility ]:
DMSO: soluble20mg/mL, clear

Click to get detail MSDS

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis.

Mol. Biol. Cell 25(18) , 2828-39, (2014)

Endoplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodegeneration, cardiovascular diseases, and diabetes. Temporally defining calcium dysregulation during...

COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells.

Exp. Cell Res. 330(2) , 451-9, (2014)

In the present study, we investigated whether celecoxib could induce the expression of NKG2D ligands in clonogenic colon cancer cells, and increase their susceptibility to NK cell-mediated cell death....

Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanisms.

Int. J. Oncol. 46(3) , 1393-404, (2015)

Celecoxib plays antitumor roles via multiple mechanisms in a variety of human cancers. The aim of this study was to clarify the mechanism of action of celecoxib in canine mammary tumors. We examined t...

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