1-Butanamine,N-ethyl-N-nitroso-
Names
[ CAS No. ]:
4549-44-4
[ Name ]:
1-Butanamine,N-ethyl-N-nitroso-
[Synonym ]:
Ethylbutylnitrosamine
N-Nitrosoethyl-N-butylamine
N-Ethyl-N-butylnitrosamine
Nitrosoethylbutylamine
N-Ethyl-N-nitrosobutylamine
Aethyl-n-butylnitrosamin
N-nitroso-N-ethylbutylamine
N-Nitroso-N-ethylbutylamine
N-Butyl-N-ethylnitrosamine
Ethyl-N-butylnitrosamine
N-Nitroso-N-butylethylamine
Butanamine,N-ethyl-N-nitroso
Butylamine,N-ethyl-N-nitroso
N-Nitroso-ethyl-butylamin
Ethyl-n-butyl-nitrosamin
N-nitrosoethylbutylamine
Ethyl-butyl-nitroso-amin
Chemical & Physical Properties
[ Density]:
0.93g/cm3
[ Boiling Point ]:
213ºC at 760mmHg
[ Molecular Formula ]:
C6H14N2O
[ Molecular Weight ]:
130.18800
[ Flash Point ]:
82.6ºC
[ Exact Mass ]:
130.11100
[ PSA ]:
32.67000
[ LogP ]:
1.78980
[ Index of Refraction ]:
1.451
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EO5075000
- CHEMICAL NAME :
- Butylamine, N-ethyl-N-nitroso-
- CAS REGISTRY NUMBER :
- 4549-44-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C6-H14-N2-O
- MOLECULAR WEIGHT :
- 130.22
- WISWESSER LINE NOTATION :
- ONN4&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 630 mg/kg/14W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1000 mg/kg/40W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg/20W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2360 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1000 mg/kg/29W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 20 gm/kg
- REFERENCE :
- ARGEAR Archiv fuer Geschwulstforschung. (VEB Verlag Volk und Gesundheit Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1949- Volume(issue)/page/year: 51,605,1981
Safety Information
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22
[ WGK Germany ]:
3
[ RTECS ]:
EO5075000
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%