3,4-epoxytetrahydrothiophene-1,1-dioxide
Names
[ CAS No. ]:
4509-11-9
[ Name ]:
3,4-epoxytetrahydrothiophene-1,1-dioxide
[Synonym ]:
3,4-epoxythiolane 1,1-dioxide
3,4-Epoxytetrahydrothiophene-1,1-dioxide
MFCD00065014
2,3-Epoxy-1,4-butanediyl sulfone
3,4-Epoxy-tetrahydro-thiophen-1,1-dioxid
2,3-Epoxytetramethylene sulfone
3,4-Epoxysulfolane
3,4-epoxy-2,3,4,5-tetrahydrothiophene-1,1-dioxide
Tetramethylene sulfone,2,3-epoxy
EINECS 224-827-3
3,4-Epoxy-1,2,3,4-tetrahydrothiophene-1,1-dioxide
Chemical & Physical Properties
[ Density]:
1.576g/cm3
[ Boiling Point ]:
379.2ºC at 760 mmHg
[ Melting Point ]:
145-150ºC(lit.)
[ Molecular Formula ]:
C4H6O3S
[ Molecular Weight ]:
134.15400
[ Flash Point ]:
183.1ºC
[ Exact Mass ]:
134.00400
[ PSA ]:
55.05000
[ LogP ]:
0.26300
[ Index of Refraction ]:
1.547
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RP3850000
- CHEMICAL NAME :
- 6-Oxa-3-thiabicyclo(3.1.0)hexane 3,3-dioxide
- CAS REGISTRY NUMBER :
- 4509-11-9
- BEILSTEIN REFERENCE NO. :
- 0113462
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C4-H6-O3-S
- MOLECULAR WEIGHT :
- 134.16
- WISWESSER LINE NOTATION :
- T35 BO ESWTJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5500 mg/kg
- TOXIC EFFECTS :
- Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
- REFERENCE :
- RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 41,257,1978 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 88 mg/kg/22W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 46,143,1971
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
20/21/22-36/37/38
[ Safety Phrases ]:
S26;S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
RP3850000
[ HS Code ]:
2902199090
Customs
[ HS Code ]: 2902199090
[ Summary ]:
2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%
Articles
J. Chem. Soc. Perkin Trans. I , 1335, (1972)
J. Chem. Soc. Chem. Commun. , 114, (1991)
Tetrahedron Lett. , 2609, (1971)