ST 045849

Names

[ Name ]:
ST 045849

Biological Activity

[Description]:

OGT-IN-2 is a O-GlcNAc transferase (OGT) inhibitor with an IC50 of 53 μM. OGT-IN-2 reduces proliferation and viability of prostate cancer cells in vitro. OGT-IN-2 depletes intracellular alanine and decreases glucose consumption by cancer cells. OGT-IN-2 decreases markers of ER stress and apoptosis in pregnant diabetic mice and reduces neural tube defects in embryos from diabetic mice.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₇ClN₂O₃S

[ Molecular Weight ]:
446.99

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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