ω-Conotoxin SO3

Names

[ Name ]:
ω-Conotoxin SO3

Biological Activity

[Description]:

ω-Conotoxin SO3 is a blocker of N-type voltage-sensitive calcium channel. ω-Conotoxin SO3 is an analgesicω-conotoxin that can be isolated from the venom of C. striatus[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Inflammation/Immunology

[References]

[1]. Wen L, et al, a new O-superfamily conopeptide derived from Conus striatus, selectively inhibits N-type calcium currents in cultured hippocampal neurons. Br J Pharmacol. 2005 Jul;145(6):728-39.

[2]. Yan LD, et al. Spinal antinociception of synthetic omega-conotoxin SO-3, a selective N-type neuronal voltage-sensitive calcium channel blocker, and its effects on morphine analgesia in chemical stimulus tests in rodent. Eur J Pharmacol. 2010 Jun 25;636(1-3):73-81.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀₀H₁₆₆N₃₆O₃₁S₆

[ Molecular Weight ]:
2561.00

Related Compounds

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