Carboxyethyl-γ-aminobutyric acid
Names
[ CAS No. ]:
4386-03-2
[ Name ]:
Carboxyethyl-γ-aminobutyric acid
[Synonym ]:
4-(2-carboxyethylamino)butanoic acid
Chemical & Physical Properties
[ Density]:
1.232g/cm3
[ Boiling Point ]:
409.2ºC at 760mmHg
[ Molecular Formula ]:
C7H13NO4
[ Molecular Weight ]:
175.18200
[ Flash Point ]:
201.3ºC
[ Exact Mass ]:
175.08400
[ PSA ]:
86.63000
[ LogP ]:
0.30640
[ Index of Refraction ]:
1.491
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EK7730000
- CHEMICAL NAME :
- Butanoic acid, 4-((2-carboxyethyl)amino)-
- CAS REGISTRY NUMBER :
- 4386-03-2
- BEILSTEIN REFERENCE NO. :
- 1774240
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H13-N-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 877 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 783 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IJBIAC Italian Journal of Biochemistry. (I1 Pensiero Scientifico Editore, Via Panama 48, I-00198 Rome, Italy) V.1- 1957- Volume(issue)/page/year: 33,31A,1984
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
EK7730000
[ HS Code ]:
2922499990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles
J. Immunol. Methods 77 , 229, (1985)
An increased proliferation of hybridomas is induced by a polyamine derivative molecule, CEGABA (carboxyethyl gamma-aminobutyric acid). The effects of CEGABA and CR-ECGS (endothelial cell growth supple...
Experimental study on central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA).Farmaco. Sci. 43(4) , 363-72, (1988)
The central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA) have been studied both in rabbits and in the guinea pig myoclonus model. This drug caused EEG synchronization and behavioural sedat...
Identification of N-carboxyethyl gamma-aminobutyric acid in bovine brain and human cerebrospinal fluid.Neurosci. Lett. 77(3) , 308-10, (1987)
The di-carboxylated derivative of spermidine, N-carboxyethyl gamma-aminobutyric acid (CEGABA) has been identified in bovine brain and human cerebrospinal fluid by HPLC. This discovery strongly suggest...