acetyl oleanolic acid

Names

[ Name ]:
acetyl oleanolic acid

[Synonym ]:
Olean-12-en-28-oic acid, 3-(acetyloxy)-, (3β)-
3-O-acetyloleanolic acid
acetyl oleanolic acid
(3β)-3-Acetoxyolean-12-en-28-oic acid
Oleanolic acid 3-acetate
Olean-12-en-28-oic acid, 3β-hydroxy-, acetate

Biological Activity

[Description]:

3-O-Acetyloleanolic acid (3AOA), an oleanolic acid derivative isolated from the seeds of Vigna sinensis K., induces in cancer and also exhibits anti-angiogenesis activity[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[Target]

Apoptosis[1].

[References]

[1]. Yoo KH, et al. 3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cells. Phytother Res. 2012 Oct;26(10):1541-6.

[2]. Hwang-Bo J, et al. 3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model. BMC Cancer. 2018 Jul 5;18(1):714.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
564.4±50.0 °C at 760 mmHg

[ Melting Point ]:
265-268 â„ƒ

[ Molecular Formula ]:
C₃₂H₅₀O₄

[ Molecular Weight ]:
498.737

[ Flash Point ]:
170.4±23.6 °C

[ Exact Mass ]:
498.370911

[ PSA ]:
63.60000

[ LogP ]:
9.95

[ Vapour Pressure ]:
0.0±3.3 mmHg at 25°C

[ Index of Refraction ]:
1.545

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.