1-Ethoxy-2,2,2-trifluoroethanol
Names
[ CAS No. ]:
433-27-2
[ Name ]:
1-Ethoxy-2,2,2-trifluoroethanol
[Synonym ]:
EINECS 207-087-6
1-Ethoxy-2,2,2-trifluoroethanol
Ethanol, 1-ethoxy-2,2,2-trifluoro-
Trifluoroacetaldehyde Ethyl HeMiacetal
MFCD00000441
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
105.0±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C4H7F3O2
[ Molecular Weight ]:
144.092
[ Flash Point ]:
39.4±0.0 °C
[ Exact Mass ]:
144.039810
[ PSA ]:
29.46000
[ LogP ]:
1.73
[ Vapour Pressure ]:
16.4±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.342
[ Storage condition ]:
0-6°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KK9000000
- CHEMICAL NAME :
- Ethanol, 1-ethoxy-2,2,2-trifluoro-
- CAS REGISTRY NUMBER :
- 433-27-2
- BEILSTEIN REFERENCE NO. :
- 0906797
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C4-H7-F3-O2
- MOLECULAR WEIGHT :
- 144.11
- WISWESSER LINE NOTATION :
- FXFFYQO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1212,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 13,1212,1970
Safety Information
[ Symbol ]:
GHS02, GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H302-H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F:Flammable;Xn:Harmful;
[ Risk Phrases ]:
R11;R22
[ Safety Phrases ]:
S16-S24-S23-S45-S36/37/39
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
KK9000000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2911000000
Synthetic Route
Customs
[ HS Code ]: 2911000000
[ Summary ]:
2911000000 acetals and hemiacetals, whether or not with other oxygen function, and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
Tetrahedron Lett. 33 , 1351, (1992)
Tetrahedron Asymmetry 2 , 235, (1991)
Tetrahedron Lett. 32 , 3823, (1991)