Ibuprofen Impurity K

Names

[ Name ]:
Ibuprofen Impurity K

[Synonym ]:
2-(4-formylphenyl)propanoic acid
Ibuprofen Impurity 11

Biological Activity

[Description]:

Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₀O₃

[ Molecular Weight ]:
178.18500

[ Exact Mass ]:
178.06300

[ PSA ]:
54.37000

[ LogP ]:
1.68720

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%