4-(Trifluoromethoxy)phenylacetic acid

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
260.6±35.0 °C at 760 mmHg

[ Melting Point ]:
85-88 °C(lit.)

[ Molecular Formula ]:
C₉H₇F₃O₃

[ Molecular Weight ]:
220.145

[ Flash Point ]:
111.4±25.9 °C

[ Exact Mass ]:
220.034729

[ PSA ]:
46.53000

[ LogP ]:
2.46

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.478

Click to get detail MSDS

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918990090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synthesis and Biological Evaluation of Fluorinated 3-Phenylcoumarin-7-O-Sulfamate Derivatives as Steroid Sulfatase Inhibitors.

Chem. Biol. Drug Des. 87 , 233-8, (2016)

In the present work, we report the initial results of our study on a series of 3-phenylcoumarin sulfamate-based compounds containing C-F bonds as novel inhibitors of steroid sulfatase. The new compoun...

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