6-Chlorouracil

Names

[ Name ]:
6-Chlorouracil

[Synonym ]:
Chlorouracil
6-Chlorpyrimidin-2,4-diol
6-Chloropyrimidine-2,4-diol
6-Chlorouracil
AURORA KA-4918
6-chloro-2,6-dihydroxypyrimidine
MFCD00014595
6-Chloropyrimidine-2,4(1H,3H)-dione
EINECS 224-258-0
6-Chloro-2,4(1H,3H)-pyrimidinedione
4-chloro-uracil
2,4(1H,3H)-Pyrimidinedione, 6-chloro-
4-Chlorouracil
6-chloropyrimidine-2,4-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
300°C

[ Melting Point ]:
290-295°C

[ Molecular Formula ]:
C₄H₃ClN₂O₂

[ Molecular Weight ]:
146.532

[ Exact Mass ]:
145.988312

[ PSA ]:
65.72000

[ LogP ]:
-0.52

[ Index of Refraction ]:
1.587

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Electron attachment to chlorouracil: a comparison between 6-ClU and 5-ClU.

J. Chem. Phys. 120 , 704-709, (2004)

Low energy electron impact to the isomers 6-chlorouracil (6-ClU) and 5-chlorouracil (5-ClU) yields a variety of negative ion fragments with surprisingly high cross sections. These ions are dominantly ...

Influence of halogenation on the properties of uracil and its noncovalent interactions with alkali metal ions. Threshold collision-induced dissociation and theoretical studies.

J. Am. Chem. Soc. 126 , 16217-16226, (2004)

The influence of halogenation on the properties of uracil and its noncovalent interactions with alkali metal ions is investigated both experimentally and theoretically. Bond dissociation energies of a...

Syntheses, pi-stacking interactions and base-pairings of uracil pyridinium salts and uracilyl betaines with nucleobases.

Org. Biomol. Chem. 4 , 3056-3066, (2006)

Reaction of 6-chlorouracil with 4-(dimethylamino)pyridine, 4-methylpyridine, and pyridin-4-yl-morpholine yielded pyridinium-substituted uracils as chlorides which were converted into pyridinium uracil...