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Dehydrodiconiferyl alcohol

Names

[ CAS No. ]:
4263-87-0

[ Name ]:
Dehydrodiconiferyl alcohol

Biological Activity

[Description]:

Dehydrodiconiferyl alcohol is an estrogen receptor agonist that can promote BMP-2-induced osteoblastogenesis. Dehydrodiconiferyl alcohol also exerts anti-inflammatory activity through inactivation of NF-κB pathways[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR
Research Areas >> Inflammation/Immunology
Research Areas >> Metabolic Disease

[References]

[1]. Lee W, et, al. Dehydrodiconiferyl alcohol promotes BMP-2-induced osteoblastogenesis through its agonistic effects on estrogen receptor. Biochem Biophys Res Commun. 2018 Jan 15;495(3):2242-2248.  

[2]. Hu X, et, al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020 Feb;72(2):305-317.  

Chemical & Physical Properties

[ Density]:
1.292g/cm3

[ Boiling Point ]:
562ºC at 760mmHg

[ Melting Point ]:
161-162℃

[ Molecular Formula ]:
C20H22O6

[ Molecular Weight ]:
358.39

[ Flash Point ]:
293.7ºC

[ Exact Mass ]:
358.14200

[ PSA ]:
88.38000

[ LogP ]:
2.62450

[ Index of Refraction ]:
1.63

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds