Ricinidine

Names

[ Name ]:
Ricinidine

[Synonym ]:
6-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
3-Pyridinecarbonitrile, 1,2-dihydro-1-methyl-2-oxo-
5-Cyano-6-hydroxy-2-picoline
3-Cyano-6-Methyl-2(1H)-Pyridinone
3-Cyano-6-methyl-2-pyridinol
1-Methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile
3-Cyano-6-Methyl-2-pyridone
MFCD00006013
Ricinidine
1-Methyl-2-pyridone-3-carbonitrile
1-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
2-Hydroxy-6-methylnicotinonitrile
6-methyl-2-oxo-1H-pyridine-3-carbonitrile
EINECS 224-202-5

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
299.7±29.0 °C at 760 mmHg

[ Melting Point ]:
293-295 °C

[ Molecular Formula ]:
C₇H₆N₂O

[ Molecular Weight ]:
134.135

[ Flash Point ]:
135.0±24.3 °C

[ Exact Mass ]:
134.048019

[ PSA ]:
56.65000

[ LogP ]:
-0.54

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.568

[ Water Solubility ]:
2.38 g/L (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S36/37/39-S26-S22-S36

[ RIDADR ]:
3276

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.

Bioorg. Med. Chem. Lett. 18(6) , 2206-10, (2008)

Tumor cells extensively utilize the pentose phosphate pathway for the synthesis of ribose. Transketolase is a key enzyme in this pathway and has been suggested as a target for inhibition in the treatm...

Construction of three-dimensional supramolecular coordination copper (I) compounds with channel structures hosting a variety of anions by changing the hydrogen-bonding mode and distances. Munakata M, et al.

J. Am. Chem. Soc. 118(13) , 3117-24, (1996)