N-aryl benzimidazole

Names

[ Name ]:
N-aryl benzimidazole

[Synonym ]:
1H-Benzimidazole-5-carboxamide, N-[(2-chlorophenyl)methyl]-1-(3-methylphenyl)-
N-(2-Chlorobenzyl)-1-(3-methylphenyl)-1H-benzimidazole-5-carboxamide
MFCD15095628

Biological Activity

[Description]:

N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.

[References]

References 1. Tardiff DF, et al. Science. 2013 Nov 22;342(6161):979-83. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C₂₂H₁₈ClN₃O

[ Molecular Weight ]:
375.851

[ Exact Mass ]:
375.113831

[ LogP ]:
5.41

[ Index of Refraction ]:
1.652

Related Compounds

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