chloroquine mustard
Names
[ CAS No. ]:
4213-44-9
[ Name ]:
chloroquine mustard
Chemical & Physical Properties
[ Molecular Formula ]:
C18H25Cl4N3
[ Molecular Weight ]:
425.22300
[ Exact Mass ]:
423.08000
[ PSA ]:
28.16000
[ LogP ]:
6.12340
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB0175000
- CHEMICAL NAME :
- Quinoline, 4-((4-(bis(2-chloroethyl)amino)-1-methylbutyl)amino)- 7-chloro-, dihydrochloride
- CAS REGISTRY NUMBER :
- 4213-44-9
- LAST UPDATED :
- 199203
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C18-H24-Cl3-N3.2Cl-H
- MOLECULAR WEIGHT :
- 461.72
- WISWESSER LINE NOTATION :
- T66 BNJ EMY1&3N2G2G &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 17,63,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 21,1124,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 200 ug/kg
- TOXIC EFFECTS :
- Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,202,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 410 ug/kg
- TOXIC EFFECTS :
- Blood - other changes
- REFERENCE :
- CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,202,1965 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8 mg/kg/4W
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 36,915,1966
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.