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6-NITRO-4-OXO-4H-CHROMENE-3-CARBALDEHYDE

Names

[ CAS No. ]:
42059-80-3

[ Name ]:
6-NITRO-4-OXO-4H-CHROMENE-3-CARBALDEHYDE

[Synonym ]:
3-Formyl-6-nitrochromone
6-Nitro-4-oxo-4H-1-benzopyran-3-carboxaldehyde
6-nitrochromone-3-carboxaldehyde
MFCD00192184
6-nitro-4-oxo-4H-benzopyran-3-carboxaldehyde
6-nitrochromone-3-carbaldehyde
6-Nitro-4-oxo-4H-chromene-3-carbaldehyde
6-nitro-3-formylchromone

Chemical & Physical Properties

[ Melting Point ]:
157-161 ℃(lit.)

[ Molecular Formula ]:
C10H5NO5

[ Molecular Weight ]:
219.15000

[ Exact Mass ]:
219.01700

[ PSA ]:
93.10000

[ LogP ]:
2.03690

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2914400090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.

In Vivo 20(5) , 645-9, (2006)

Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relati...

Biological activity of 3-formylchromones and related compounds.

In Vivo 21(5) , 829-34, (2007)

Several 3-formylchromone derivatives were examined for their tumor cell-cytotoxic, anti-Helicobacter pylori, urease inhibitory and anti-HIV activity. Comparing their relative cytotoxicity against four...

Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library.

Chem. Biol. 11(3) , 337-45, (2004)

The polypeptide N-acetyl-alpha-galactosaminyltransferases (ppGalNAcTs, also abbreviated ppGaNTases) initiate mucin-type O-linked glycosylation and therefore play pivotal roles in cell-cell communicati...


More Articles


Related Compounds

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