Sodium tauroglycocholate

Names

[ CAS No. ]:
41945-48-6

[ Name ]:
Sodium tauroglycocholate

[Synonym ]:
einecs 255-596-7
Sodium 2-({N-[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycyl}amino)ethanesulfonate
Ethanesulfonic acid, 2-[[2-[[(3α,5β,7α,8ξ,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]acetyl]amino]-, sodium salt (1:1)
Ethanesulfonic acid, 2-(((((3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)acetyl)amino)-, monosodium salt

Biological Activity

[Description]:

Sodium tauroglycocholate is an inhibitor of the biliary acid transporting system of the hepatocyte and also a surfactant used as a chemical permeation enhancer.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Endocrinology

[References]

[1]. Schuhmann-Giampieri G, et al. Biliary excretion and pharmacokinetics of a gadolinium chelate used as a liver-specific contrast agent for magnetic resonance imaging in the rat. J Pharm Sci. 1993 Aug;82(8):799-803.

[2]. Kouchak M, et al. Effects of various penetration enhancers on penetration of aminophylline through shed snake skin. Jundishapur J Nat Pharm Prod. 2014 Feb;9(1):24-9.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₄₇N₂NaO₈S

[ Molecular Weight ]:
594.736

[ Exact Mass ]:
594.295105

[ PSA ]:
184.47000

[ LogP ]:
3.00430

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
2918290000

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Related Compounds

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