O-Methyl-L-threonine

Names

[ CAS No. ]:
4144-02-9

[ Name ]:
O-Methyl-L-threonine

[Synonym ]:
L-Threonine methyl ether
O-METHYL-L-THREONINE
MFCD00037767
L-Thr(me)

Biological Activity

[Description]:

H-Thr(Me)-OH is a threonine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.143g/cm3

[ Boiling Point ]:
248ºC at760mmHg

[ Molecular Formula ]:
C₅H₁₁NO₃

[ Molecular Weight ]:
133.14600

[ Flash Point ]:
103.8ºC

[ Exact Mass ]:
133.07400

[ PSA ]:
72.55000

[ LogP ]:
0.13350

[ Index of Refraction ]:
1.461

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Inhibitors of specific aminoacyl-tRNA synthetases prevent thyrotropin-induced desensitization in cultured human thyroid cells.

J. Biol. Chem. 257(3) , 1342-6, (1982)

Autonomous synthesis of alpha and beta hemoglobin chains in rabbit erythroid cells.

Blood 57(6) , 1125-31, (1981)

Hemoglobin beta-chain synthesis by rabbit erythroid cells was tested for dependence on availability of complementary alpha-chains. Reticulocytes and bone marrow cells were obtained from variant rabbit...

Related Compounds

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