BAM(8-22)

Names

[ Name ]:
BAM(8-22)

[Synonym ]:
bam8-22

Biological Activity

[Description]:

BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Parul Sikand, et al. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. J Neurosci. 2011 May 18;31(20):7563-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉₁H₁₂₇N₂₅O₂₃S

[ Molecular Weight ]:
1971.20000

[ Exact Mass ]:
1969.93000

[ PSA ]:
826.78000

[ LogP ]:
5.47110

Related Compounds

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