D-Glucose-13C-4

Names

[ Name ]:
D-Glucose-13C-4

[Synonym ]:
C1-13C-D-glucose
MFCD00037545

Biological Activity

[Description]:

D-Glucose-13C-4 (Glucose-13C-4) is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Melting Point ]:
150-152ºC(lit.)

[ Molecular Formula ]:
C₅₁₃CH₁₂O₆

[ Molecular Weight ]:
181.14900

[ Exact Mass ]:
181.06700

[ PSA ]:
110.38000

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Articles

Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis.

Nucleic Acids Res. 39(20) , 8992-9008, (2011)

Iron-inducible transcription of the ap65-1 gene in Trichomonas vaginalis involves at least three Myb-like transcriptional factors (tvMyb1, tvMyb2 and tvMyb3) that differentially bind to two closely sp...