3-Methylpyrazole-4-carboxylic acid

Names

[ CAS No. ]:
40704-11-8

[ Name ]:
3-Methylpyrazole-4-carboxylic acid

[Synonym ]:
3-Methyl-1H-Pyrazole-4-Carboxylic Acid
MFCD00608153

Chemical & Physical Properties

[ Density]:
1.404g/cm3

[ Boiling Point ]:
384.2ºC at 760 mmHg

[ Melting Point ]:
225-230ºC (dec.)(lit.)

[ Molecular Formula ]:
C₅H₆N₂O₂

[ Molecular Weight ]:
126.11300

[ Flash Point ]:
186.1ºC

[ Exact Mass ]:
126.04300

[ PSA ]:
65.98000

[ LogP ]:
0.41630

[ Index of Refraction ]:
1.595

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933199090

[ Summary ]:
2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma D-tryptophan.

Proc. Jpn. Acad.,. Ser. B, Phys. Biol. Sci. 10th ed., 87 , 641-8, (2011)

A determination method for 3-methylpyrazole-5-carboxylic acid (MPC), an inhibitor of D-amino acid oxidase (DAAO), in rat plasma was developed by using high-performance liquid chromatography-mass spect...

A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity.

Biomed. Chromatogr. 30 , 384-9, (2016)

Elution profiles of kynurenic acid (KYNA) and 7-chlorokynurenic acid (Cl-KYNA) were examined by high-performance liquid chromatography (HPLC) using a triazole-bonded stationary phase column (Cosmosil®...