Tetrahydro-2-(bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorin-4-ol 2-oxide
Names
[ CAS No. ]:
40277-05-2
[ Name ]:
Tetrahydro-2-(bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorin-4-ol 2-oxide
[Synonym ]:
4-Hydroxycyclophosphamid
4-Hydroperoxydechlorocyclophosphamide
4-Hydroxycyclophosphamide
2-[bis(2-chloroethyl)amino]-2-oxo-1,3,2λ<sup>5</sup>-oxazaphosphinan-4-ol
4-OH cyclophosphamide
Chemical & Physical Properties
[ Density]:
1.42g/cm3
[ Boiling Point ]:
387.1ºC at 760 mmHg
[ Molecular Formula ]:
C7H15Cl2N2O3P
[ Molecular Weight ]:
277.08500
[ Flash Point ]:
187.9ºC
[ Exact Mass ]:
276.02000
[ PSA ]:
71.61000
[ LogP ]:
1.53120
[ Index of Refraction ]:
1.527
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RP6162000
- CHEMICAL NAME :
- 2H-1,3,2-Oxazaphosphorin-4-ol, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide
- CAS REGISTRY NUMBER :
- 40277-05-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H15-Cl2-N2-O3-P
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
Safety Information
[ HS Code ]:
2934999090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%