STAT3-IN-24, cell-permeable

Names

[ Name ]:
STAT3-IN-24, cell-permeable

Biological Activity

[Description]:

STAT3-IN-24, cell-permeable (PpYLKTK-mts) is a STAT3 peptide inhibitor. STAT3-IN-24, cell-permeable inhibits recruitment of STAT3 to Jak2 and phosphorylation of Y705, thus preventing the dimerization and the nuclear translocation of STAT3[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> STAT

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> STAT

[References]

[1]. Buettner C, et al. Critical role of STAT3 in leptin's metabolic actions. Cell Metab. 2006 Jul;4(1):49-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉₂H₁₅₇N₂₀O₂₄P

[ Molecular Weight ]:
1958.32