Mephentermine Hydrochloride

Names

[ Name ]:
Mephentermine Hydrochloride

[Synonym ]:
N,2-dimethyl-1-phenylpropan-2-amine,hydrochloride

Biological Activity

[Description]:

Mephentermine (hydrochloride) can increase peripheral resistance significantly. Mephentermine (hydrochloride) can be used in the research of cardiovascular areas[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Thorkild W. Andersen, et al. Mephentermine and ephedrine in man: A comparative study on cardiovascular effects. Clin Pharmacol Ther. 1964, 281, 5.

Chemical & Physical Properties

[ Boiling Point ]:
229.4ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₈ClN

[ Molecular Weight ]:
199.72000

[ Flash Point ]:
90ºC

[ Exact Mass ]:
199.11300

[ PSA ]:
12.03000

[ LogP ]:
3.42000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA0348400

CHEMICAL NAME :: Benzeneethanamine, N,alpha,alpha-trimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 3978-34-5

LAST UPDATED :: 199303

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H17-N.Cl-H

MOLECULAR WEIGHT :: 199.75

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - Straub tail Gastrointestinal - changes in structure or function of salivary glands Skin and Appendages - hair

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 15,304,1969