(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol

Names

[ CAS No. ]:
391901-45-4

[ Name ]:
(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol

[Synonym ]:
Benzenemethanol, α-[[[2-(4-aminophenyl)ethyl]amino]methyl]-, (αR)-
(1R)-2-[[2-(4-aminophenyl)ethyl]amino]-1-phenylethanol
(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol
(R)-2-(4-aminophenylethylamine)-1-phenylethanol
Mirabegron Impurity 6
YM-208876
(R)-2-[[2-(4-aminophenyl)ethyl]amino]-1-phenylethanol
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol
(1 R)-2-[(4-aminophenethyl)amino]-1-phenyl-1-ethanol

Biological Activity

[Description]:

Mirabegron impurity-1 is a potent and selectiveβ3- adrenergic receptor agonist. Mirabegron impurity-1has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used inthe study of the treatment of bladder impurity [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Takusagawa S, et al. Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist. Xenobiotica. 2012 Oct;42(10):957-67.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
447.9±24.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₀N₂O

[ Molecular Weight ]:
256.34

[ Flash Point ]:
224.7±22.9 °C

[ Exact Mass ]:
256.157562

[ PSA ]:
58.28000

[ LogP ]:
1.45

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.618