4-((3-((2-Chloroethyl)amino)propyl)amino)-7-trifluoromethylquinoline d ihydrochloride
Names
[ CAS No. ]:
38914-93-1
[ Name ]:
4-((3-((2-Chloroethyl)amino)propyl)amino)-7-trifluoromethylquinoline d ihydrochloride
[Synonym ]:
4-((3-((2-Chloroethyl)amino)propyl)amino)-7-trifluoromethylquinoline dihydrochloride
ICR 380
n-(2-chloroethyl)-n'-[7-(trifluoromethyl)quinolin-4-yl]propane-1,3-diamine dihydrochloride
1,3-Propanediamine,N-(2-chloroethyl)-N'-(7-(trifluoromethyl)-4-quinolinyl)-,dihydrochloride
Quinoline,4-((3-((2-chloroethyl)amino)propyl)amino)-7-trifluoromethyl-,dihydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
454.8ºC at 760mmHg
[ Molecular Formula ]:
C15H19Cl3F3N3
[ Molecular Weight ]:
404.68600
[ Flash Point ]:
228.9ºC
[ Exact Mass ]:
403.06000
[ PSA ]:
36.95000
[ LogP ]:
5.95190
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX7098000
- CHEMICAL NAME :
- 1,3-Propanediamine, N-(2-chloroethyl)-N'-(7-(trifluoromethyl)-4-quinoliny l)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 38914-93-1
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H17-Cl-F3-N3.2Cl-H
- MOLECULAR WEIGHT :
- 404.72
- WISWESSER LINE NOTATION :
- T66 BNJ EM3M2G IXFFF &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD20 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 101 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,739,1972