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Hexa-N-acetylchitohexaose

Names

[ CAS No. ]:
38854-46-5

[ Name ]:
Hexa-N-acetylchitohexaose

[Synonym ]:
glcnac-beta1-4glcnac-beta1-4glcnac-beta1-4glcnac-beta1-4glcnac-beta1-4glcnac

Biological Activity

[Description]:

Hexa-N-acetylchitohexaose is an inducer of disease resistance in crop plants, which could elicit an increase of lignification-related and antioxidative enzymes in soybean plants. Hexa-N-acetylchitohexaose is a substrate of lysozyme. Hexa-N-acetylchitohexaose shows antitumor effect[1][2][3].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vivo]

On sarcoma 180 solid tumor in ddY mice using lentinan, an antitumorβ-D-glucan, as the positive control. Hexa-N-acetylchitohexaose (100 mg/kg/day; 3 times; intravenous ) significantly inhibits the growth of this allogenic solid tumor, affording a high tumor growth-inhibition ratio (85%) at 7 days after tumor implantation[3].

[References]

[1]. Li K, et al. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation. Biomed Res Int. 2017;2017:2486515.

[2]. David C. Phillips. THE HEN EGG-WHITE LYSOZYME MOLECULE. Proc Natl Acad Sci U S A. 1967 Mar; 57(3): 483-495.

[3]. Suzuki K, et al. Antitumor effect of hexa-N-acetylchitohexaose and chitohexaose. Carbohydr Res. 1986;151:403-408.

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Boiling Point ]:
1652.6ºC at 760mmHg

[ Melting Point ]:
>250°C (dec.)

[ Molecular Formula ]:
C48H80N6O31

[ Molecular Weight ]:
1237.17000

[ Flash Point ]:
953.3ºC

[ Exact Mass ]:
1236.49000

[ PSA ]:
559.35000

[ Index of Refraction ]:
1.633

Safety Information

[ Safety Phrases ]:
24/25

[ WGK Germany ]:
3

[ RTECS ]:
LZ6653000

Related Compounds