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Tetrahydroepiberberine

Names

[ CAS No. ]:
38853-67-7

[ Name ]:
Tetrahydroepiberberine

[Synonym ]:
8,9-Dimethoxy-6,11,12,14-tetrahydro-6aH-[1,3]dioxolo[4,5-h]isoquinolino[2,1-b]isoquinoline
(+)-Tetrahydroepiberberine
2,3-dimethoxy-9,10-methylenedioxyberbine
12H-Benzo[a]-1,3-benzodioxolo[4,5-g]quinolizine, 6,6a,11,14-tetrahydro-8,9-dimethoxy-
Sinactin

Biological Activity

[Description]:

Tetrahydroepiberberine is a isoquinoline alkaloid isolated from Corydalis impatiens (Pall). Tetrahydroepiberberine has antifungal and selective inhibition against the PI-3 virus activities[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Niu X, et al. Simultaneous quantification of 11 isoquinoline alkaloids in Corydalis impatiens (Pall.) Fisch by HPLC. J Sep Sci. 2013 Jul;36(13):2090-5. 

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
470.9±45.0 °C at 760 mmHg

[ Melting Point ]:
170 - 172 °C (甲醇),183 - 184 °C (乙醇)

[ Molecular Formula ]:
C20H21NO4

[ Molecular Weight ]:
339.385

[ Flash Point ]:
139.2±25.9 °C

[ Exact Mass ]:
339.147064

[ PSA ]:
40.16000

[ LogP ]:
3.83

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.656

[ Water Solubility ]:
Practically insoluble (0.085 g/L) (25 ºC)

Related Compounds