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Asatone

Names

[ CAS No. ]:
38451-63-7

[ Name ]:
Asatone

Biological Activity

[Description]:

Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

NF-κB[1]


[References]

[1]. Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671.

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
536.1ºC at 760 mmHg

[ Molecular Formula ]:
C24H32O8

[ Molecular Weight ]:
448.50600

[ Flash Point ]:
228.9ºC

[ Exact Mass ]:
448.21000

[ PSA ]:
89.52000

[ LogP ]:
2.35650

[ Index of Refraction ]:
1.533

Synthetic Route

Precursor & DownStream