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Bimatoprost acid methyl ester

Names

[ CAS No. ]:
38315-47-8

[ Name ]:
Bimatoprost acid methyl ester

[Synonym ]:
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, methyl ester, (5Z)-
Methyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl}hept-5-enoate
BiMatoprost Acid Methyl Ester
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-(E)-3-hydroxy-5-phenylpent-1-enyl)-cyclopentyl]hept-5-enoic acid methyl ester
Methyl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl}-5-heptenoate
(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-; 2-((E)-(S)-3-hydroxy-5-phenyl-pent-; 1-enyl)-cyclopentyl]-hept-5-enoic a; cid methyl ester
(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid methylester
methyl ester of bimatoprost acid

Biological Activity

[Description]:

Bimatoprost methyl ester is a prodrug of Bimatoprost (HY-B0191)[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Others >> Others

[References]

[1]. Balapure AK, et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38(14):2375-81.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
557.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H34O5

[ Molecular Weight ]:
402.524

[ Flash Point ]:
184.0±23.6 °C

[ Exact Mass ]:
402.240631

[ PSA ]:
86.99000

[ LogP ]:
2.68

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.591

Precursor & DownStream

Precursor

DownStream

Related Compounds