Todralazine hydrochloride

Names

[ Name ]:
Todralazine hydrochloride

[Synonym ]:
3-Phthalazin-1-yl-carbazidsaeure-aethylester,Hydrochlorid
Todralazine HCl
Apirachol
Ecarazine
Todralazine hydrochloride
3-phthalazin-1-yl-carbazic acid ethyl ester,hydrochloride
Ecarazine hydrochloride
Binazine
Binazin
621-BT hydrochloride

Biological Activity

[Description]:

Todralazine hydrochloride (Ecarazine hydrochloride) is an anti-hypertensive agent, acts as a β2AR blocker, with antioxidant and free radical scavenging activity[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[Target]

β2AR[1]

[References]

[1]. Dimri M, et al. Todralazine protects zebrafish from lethal effects of ionizing radiation: role of hematopoietic cell expansion. Zebrafish. 2015 Feb;12(1):33-47.

Chemical & Physical Properties

[ Density]:
1.328g/cm3

[ Molecular Formula ]:
C₁₁H₁₃ClN₄O₂

[ Molecular Weight ]:
268.70000

[ Exact Mass ]:
268.07300

[ PSA ]:
76.14000

[ LogP ]:
2.96870

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
36

[ WGK Germany ]:
3

[ RTECS ]:
FE2778600

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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