Rhodojaponin V

Names

[ Name ]:
Rhodojaponin V

[Synonym ]:
5,6,10,16-Tetrahydroxy-2,3-epoxygrayanotoxan-14-yl acetate
Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 14-acetate

Biological Activity

[Description]:

Rhodojaponin V is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Zhou J, et al. Anti-inflammatory Grayanane Diterpenoids from the Leaves of Rhododendron molle. J Nat Prod. 2018 Jan 26;81(1):151-161.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
551.8±50.0 °C at 760 mmHg

[ Melting Point ]:
232 °C

[ Molecular Formula ]:
C₂₂H₃₄O₇

[ Molecular Weight ]:
410.501

[ Flash Point ]:
187.5±23.6 °C

[ Exact Mass ]:
410.230438

[ PSA ]:
119.75000

[ LogP ]:
1.51

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.603

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ME1110000

CHEMICAL NAME :: Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 14-acetate, (2-beta,3-beta,6-beta,14R)-

CAS REGISTRY NUMBER :: 37720-86-8

LAST UPDATED :: 199203

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H34-O7

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 35,303,1976

Related Compounds

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